UPSC Medical Science Syllabus

          UPSC Medical Science Syllabus for Paper 1

1. Applied anatomy including blood and nerve supply of upper and lower limbs and joints of shoulder, hip, and knee. 
2. Gross anatomy, blood supply, and lymphatic drainage of tongue, thyroid, mammary gland, stomach, liver, prostate, gonads, and uterus. 
3. Applied anatomy of the diaphragm, perineum, and inguinal region. 
4. Clinical anatomy of kidney, urinary bladder, uterine tubes, vas deferens. 
5. Embryology: Placenta and placental barrier. Development of heart, gut, and kidney. uterus, ovary, testis, and their common congenital abnormalities. 
6. Central and Peripheral Autonomic Nervous System: Gross and clinical anatomy of ventricles of the brain, circulation of cerebrospinal fluid; Neural pathways and lesions of cutaneous sensations, hearing and vision; Cranial nerves distribution and clinical significance; Components of the autonomic nervous system.

1. Conduction and transmission of impulse, mechanism of contraction, neuromuscular transmission, reflexes, control of equilibrium, posture and muscle tone, descending pathways, functions of the cerebellum, basal ganglia, Physiology of sleep and consciousness. 
2. Endocrine System: Mechanism of action of hormones; formation, secretion, transport, metabolism, function, and regulation of secretion of pancreas and pituitary gland. 
3. Physiology of Reproductive System: Pregnancy menstrual cycle, lactation, pregnancy. 
4. Blood: Development, regulation, and fate of blood cells. 
5. Cardio-vascular, cardiac output, blood pressure, regulation of cardiovascular functions.

1. Organ function tests—liver, kidney, thyroid Protein synthesis. Vitamins and minerals. 
2. Restriction fragment length. 
3. Polymorphism (RFLP). 
4. Polymerase chain reaction (PCR). Radio-immunoassays (RIA).

1. Inflammation and repair, disturbances of growth and cancer, Pathogenesis and histopathology of rheumatic and ischaemic heart disease and diabetes mellitus. Differentiation between benign, malignant, primary, and metastatic malignancies, Pathogenesis and histopathology of bronchogenic carcinoma, carcinoma breast, oral cancer, cancer cervix, leukemia, Etiology, pathogenesis and histopathology of—cirrhosis liver, glomerulonephritis, tuberculosis, acute osteomyelitis.

1. Humoral and cell-mediated immunity. 
2. Diseases caused by and laboratory diagnosis of — 
   1. Meningococcus, Salmonella 
   2. Shigella, Herpes, Dengue, Polio  
   3. HIV/AIDS, Malaria, E. Histolytica, Giardia 
   4. Candida, Cryptococcus, Aspergillus.

1. Mechanism of action and side effects of the following drugs:
   1. Antipyretics and analgesics, Antibiotics
   2. Antimalaria, Anti kala-azar, Antidiabetics
   3. Antihypertensive, Antidiuretics, General and cardiac vasodilators, Antiviral, Antiparasitic, Antifungal, Immunosuppressants
   4. Anticancer.

1. Forensic examination of injuries and wounds; Examination of blood and seminal stains; Poisoning, sedative overdose, hanging, drowning, burns, DNA and fingerprint study.

        UPSC Medical Science Syllabus for Paper 2

1. Etiology, clinical features, diagnosis, and principles of management (including prevention) of—Typhoid, Rabies, AIDS, Dengue, Kala-azar, and Japanese Encephalitis. 
2. Etiology, clinical features, diagnosis, and principles of management of: 
3. Ischaemic heart disease, pulmonary embolism. 
4. Bronchial asthma. 
5. Pleural effusion, tuberculosis, Malabsorption syndromes; acid peptic diseases, Viral hepatitis, and cirrhosis of the liver. 
6. Glomerulonephritis and pyelonephritis, renal failure, nephrotic syndrome, renovascular hypertension, complications of diabetes mellitus, coagulation disorders, leukemia, Hypo and hyperthyroidism, meningitis, and encephalitis. 
7. Imaging medical problems, ultrasound, echocardiogram, CT scan, MRI. 
8. Anxiety and Depressive Psychosis and schizophrenia and ECT.

1. Immunization, Baby friendly hospital, congenital cyanotic heart disease, respiratory distress syndrome, broncho—pneumonia, kernicterus. IMNCI classification and management, PEM grading and management. ARI and Diarrhea of under-five and their management.

1. Psoriasis, Allergic dermatitis, scabies, eczema, vitiligo, Steven Johnson’s syndrome, Lichen Planus.

1. Clinical features, causes, diagnosis, and principles of management of cleft palate, harelip. 
2. Laryngeal tumor, oral and oesophageal tumors. 
3. Peripheral arterial diseases, varicose veins, coarctation of aorta. 
4. Tumours of the Thyroid, Adrenal, and Glands. 
5. Abscess cancer, fibroadenoma, and adenosis of the breast. 
6. Bleeding peptic ulcer, tuberculosis of the bowel, ulcerative colitis, cancer of the stomach. 
7. Renal mass, cancer prostate. 
8. Haemothorax, stones of the Gall bladder, Kidney, Ureter, and Urinary Bladder. 
9. Management of surgical conditions of the Rectum, Anus, Anal canal, Gall bladder, and Bile ducts. 
10. Splenomegaly, cholecystitis, portal hypertension, liver abscess, peritonitis, carcinoma head of the pancreas. 
11. Fractures of the spine, Colles’ fracture, and bone tumors. 
12. Endoscopy. 
13. Laparoscopic Surgery.

1. Diagnosis of pregnancy. 
2. Labour management, complications of 3rd stage, Antepartum, and postpartum hemorrhage, resuscitation of the newborn, Management of abnormal life, and difficult labor. Management of small date or premature newborns. 
3. Diagnosis and management of anemia. Preeclampsia and Toxemia of pregnancy, Management of Post-menopausal Syndrome. 
4. Intra-uterine devices, pills, tubectomy, and vasectomy. Medical termination of pregnancy including legal aspects. 
5. Cancer cervix. 
6. Leucorrhoea, pelvic pain; infertility, dysfunctional uterine bleeding (DUB), amenorrhoea, Fibroid, and prolapse of uterus.

1. Principles, methods, approach, and measurements of Epidemiology. 
2. Nutrition, nutritional diseases/disorders, and Nutrition Programmes. 
3. Health information Collection, Analysis, and Presentation. 
4. Objectives, components, and critical analysis of National programs for control/eradication of: 
5. Malaria, Kala-azar, Filaria and Tuberculosis, 
6. HIV/AIDS, STDs, and Dengue. 
7. Critical appraisal of the Health care delivery system. 
8. Health management and administration; Techniques, Tools, Programme Implementation and Evaluation. 
9. Objectives, Components, Goals, and Status of Reproductive and Child Health, National Rural Health Mission, and Millennium Development Goals. 
10. Management of hospital and industrial waste.

• Human Anatomy by B D Chaurasia
• Human Physiology by Ganong; Guyton and A.K. Jain 
• Microbiology by D R Arora
• Biochemistry by U. Satyanarayana 
• Textbook of Pathology by Harsh Mohan
• Essentials of Medical Pharmacology by K D Tripathi
• Illustrated Reviews Pharmacology by Lippincott
• Essentials of Forensic Medicine and Toxicology by Dr K S Narayan Reddy
• Pathology by Robbins and Cotran
• Embryology from I B Singh

• General Medicine textbook of medicine by S N Chugh
• Essential pediatrics by O P Ghai, Paul, and Bagga.
• Illustrated Synopsis of Dermatology and Sexually Transmitted Diseases by Dr Neena Khanna.
• Manipal Manual of Surgery by K. Rajgopal Shenoy
• Emergency medicine by S N Chugh
• Medicine: Prep Manual for Undergraduates by George Mathews
• Clinical surgery by S Das.
• Practical Aspects of Pediatrics by Dr Mayoor K Chheda